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What Is Linalool?

Linalool is a terpene with a floral and spicy aroma. It is found in large concentrations in lavender and is the main component of lavender essential oils. Lavender has traditionally been used therapeutically to aid sleep and to help calm anxiety. Studies have found that linalool is responsible for these therapeutic benefits. If you have an allergy to lavender, we recommend avoiding strains with linalool. Linalool is commonly used for its floral fragrance in different commercial products. The presence of this terpene in cannabis may contribute to the calming and sedating effects of certain strains. 

Lavender (Off2riorob, CC BY-SA 3.0, via Wikimedia Commons)

Where is Linalool Found?

Lavender flower is the most common plant with linalool, but it is found in other plants such as honeysuckle, ginger, and hops. This terpene is used as a fragrance for personal care products such as deodorant, perfume, soap, moisturizers, make-up, and more. Cleaning products, air fresheners, and insect repellent can also contain linalool. Linalool is also one of the terpenes in cocoa beans, so there may be a small amount of it in our chocolates.

Potential Therapeutic Benefits

Cultivars with Linalool

LA flower with 0.41% linalool
LA Kush Cake
thunder struck flower with 0.25% linalool
Thunder Struck
orange kush cake .2% Linalool
Orange Kush Cake

References

  • Białoń, M., Krzyśko-Łupicka, T., Nowakowska-Bogdan, E., & Wieczorek, P. P. (2019). Chemical composition of two different lavender essential oils and their effect on facial skin microbiota. Molecules, 24(18), 3270. https://doi.org/10.3390/molecules24183270
  • Bonvehí, J. S. (2005). Investigation of aromatic compounds in roasted cocoa powder. European Food Research and Technology, 221(1-2), 19–29. https://doi.org/10.1007/s00217-005-1147-y
  • Buchbauer, G., Jirovetz, L., Jäger, W., Dietrich, H., & Plank, C. (1991). Aromatherapy: evidence for sedative effects of the essential   oil of lavender after inhalation. Zeitschrift fur Naturforschung. C, Journal of Biosciences, 46(11-  12), 1067–1072.   https://doi.org/10.1515/znc-1991-11-1223
  • Cannacon. (2019). Terpene Profiles in Chocolates. CannaCon. Retrieved November 14, 2022, from https://cannacon.org/terpene-profiles-in-chocolates/
  • Elisabetsky, E., Brum, L. F., & Souza, D. O. (1999). Anticonvulsant properties of linalool in glutamate-related seizure models. Phytomedicine: International Journal of Phytotherapy and Phytopharmacology, 6(2), 107–113. https://doi.org/10.1016/s0944-7113(99)80044-0
  • Gu, Y., Ting, Z., Qiu, X., Zhang, X., Gan, X., Fang, Y., Xu, X., & Xu, R. (2010). Linalool preferentially induces robust apoptosis of a   variety of leukemia cells via upregulating p53 and cyclin-dependent kinase inhibitors. Toxicology, 268(1-2), 19–24. https://  doi.org/10.1016/j.tox.2009.11.013
  • Guo, F., Chen, Q., Liang, Q., Zhang, M., Chen, W., Chen, H., Yun, Y., Zhong, Q., & Chen, W. (2021). Antimicrobial Activity and Proposed Action Mechanism of Linalool Against Pseudomonas fluorescens. Frontiers in Microbiology, 12, 562094. https://doi.org/10.3389/fmicb.2021.562094
  • Guzmán-Gutiérrez, S. L., Bonilla-Jaime, H., Gómez-Cansino, R., & Reyes-Chilpa, R. (2015). Linalool and β-pinene exert their antidepressant-like activity through the monoaminergic pathway. Life Sciences, 128, 24–29. https://doi.org/10.1016/j.lfs.2015.02.021
  • Harada, H., Kashiwadani, H., Kanmura, Y., & Kuwaki, T. (2018). Linalool odor-induced anxiolytic effects in mice. Frontiers in   Behavioral Neuroscience, 12. https://doi.org/10.3389/fnbeh.2018.00241
  • Heuberger, E., Redhammer, S., & Buchbauer, G. (2004). Transdermal absorption of (-)-linalool induces autonomic deactivation but has no impact on ratings of well-being in humans. Neuropsychopharmacology: Official Publication of the American College of Neuropsychopharmacology, 29(10), 1925–1932. https://doi.org/10.1038/sj.npp.1300521+F18
  • Kamatou, G. P., & Viljoen, A. M. (2008). Linalool – a review of a biologically active compound of commercial importance. Natural   Product Communications, 3(7). https://doi.org/10.1177/1934578×0800300727
  • Linalool – whatsinproducts.com. (n.d.). Retrieved April 13, 2022, from https://www.whatsinproducts.com/chemicals/  view/1/2771/000078-70-6
  • Linck, V. M., da Silva, A. L., Figueiró, M., Piato, A. L., Herrmann, A. P., Dupont Birck, F., Caramão, E. B., Nunes, D. S.,   Moreno, P. R.,   & Elisabetsky, E. (2009). Inhaled linalool-induced sedation in mice. Phytomedicine: International Journal of Phytotherapy and Phytopharmacology, 16(4), 303–307. https://doi.org/10.1016/j.phymed.2008.08.001
  • Miyashita, M., & Sadzuka, Y. (2013). Effect of linalool as a component of Humulus lupulus on doxorubicin-induced antitumor   activity. Food and Chemical Toxicology : An International Journal Published for the British Industrial Biological Research   Association, 53, 174–179. https://doi.org/10.1016/j.fct.2012.11.035
  • National Center for Biotechnology Information (2022). PubChem Compound Summary for CID 6549, Linalool. Retrieved March 22,   2022 from https://pubchem.ncbi.nlm.nih.gov/compound/Linalool.
  • Peana, A. T., D’Aquila, P. S., Panin, F., Serra, G., Pippia, P., & Moretti, M. D. (2002). Anti-inflammatory activity of linalool and linalyl acetate constituents of essential oils. Phytomedicine: International Journal of Phytotherapy and Phytopharmacology, 9(8), 721–726. https://doi.org/10.1078/094471102321621322
  • Seol, G. H., Kang, P., Lee, H. S., & Seol, G. H. (2016). Antioxidant activity of linalool in patients with carpal tunnel syndrome. BMC Neurology, 16, 17. https://doi.org/10.1186/s12883-016-0541-3

Updated 11/15/2022

Linalool

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